Ashoka Bindusara Maurya The Great Indian Emperor History Essay

Ashoka Bindusara Maurya The Great Indian Emperor History Essay Ashoka Bindusara Maurya, the great Indian emperor was a ruler during the Maurya dynasty, born in 265 BC to parents Bindusara and Dharma Maurya (Iloveindia.com, 2010). Ashoka’s regime spread across most of India and modern Pakistan and Afghanistan which was due to a number of successful conquests that will be mentioned later. His name is often followed by the title â€Å"the great† mainly due to the fact that he was one of India’s greatest rulers. His regime saw most on India united as one state under a democratic government. His name Ashoka is Sanskrit for â€Å"without sorrow.† According to Iloveindia.com (2010), from a young age, Ashoka was quite a handful; he often got into trouble for beating up his fellow children and being cruel to animals but on the other hand was an extremely clever child who grasped all that he was taught, be it ancient Buddhist teachings or how to hunt for wild animals. By the time he was a teenager, he had his older brotherâ₠¬â„¢s complaining to their parents and this got him sent away to the outskirts of the empire to pose as a general. Here he did things as he pleased, terrorizing small communities and various would be vigilante groups. At this time, young Ashoka realized that he’s brothers were against him so when he was sent away by his father; he instead exiled himself to Kalinga where he’s greatest military conquest lay (Iloveindia.com, 2010). There he met a young maiden named Kaurwaki whom he got involved with but later abandoned. After two years in exile, Ashoka grudgingly returned to India where his father needed him to preside over a conflict in the Ujjain region. This conflict is what launched Ashoka’s devotion to Buddhism. While peace keeping, Ashoka was injured and fortunately secretly tended to by Buddhist priests who did not want the news of his injury to reach his vengeful brothers (Wold, 2010). During this period, he got to learn of ancient Buddhist teachings and va lues that helped cultivate his belief. In addition, he also met another young girl whom he married as his first wife. Years after, the conflict between the siblings climaxed when their father passed away in 268 BC leaving them battling for the emperorship. After two long years of gross violence, Ashoka finally emerged victorious to sit on the much coveted throne (Sahu, 2005). Legend has it that Ashoka killed most of his brother while most of the retreated to various parts of India. After eight years of devoted and vigilant governance, Ashoka decided to expand his empire by invading Kalinga and annexing it to India. According to Munshi (1968) this was after he had successfully imperialized the borders of Iran, Afghanistan, west Bangladesh and eastern Burma. In 286 BC, Ashoka led the Indian army into Kalinga. Regardless of Ashoka having sentimental ties to Kalinga, Kaurwaki in particular, he plunged into war head first sparing no one. The region of Kalinga though greatly betrayed and dismayed fought back bravely but ultimately lost the war (Sahu, 2005). The morning after, Ashoka visited the battle field to view the extent of his â€Å"victory† but he somewhat did not feel good about it. Seeing to houses burned to ashes and bodies lying everywhere, Ashoka was horror struck by the sight. At that moment in time, Ashoka had an epiphany where he began to be aware of and regret the horrors of his actions. Corpses lay scattered on the earth, orphaned children cried for their mother all over, widows grieved for their husbands, the Daya River ran red with blood and various temples and monuments were destroyed in the nasty brawl.

Hybridoma technology Essay Example | Topics and Well Written Essays - 1500 words

Hybridoma technology - Essay Example This proposal is still being pursued today since antibodies combine specificity (the ability to exquisitely discriminate diverse harmful molecules) and affinity (the ability to tightly lock onto those targets) with the ability to recruit effector functions of the immune system such as antibody- and complement-mediated cytolysis and antibody-dependent cell-mediated cytotoxicity (ADCC). In the alternative, a "toxic payload" (such as a radioactive element or a plant toxin) attached to the antibody can be accurately delivered to the target. This makes them suitable for homing in on and killing cancer cells, infectious diseases as well as modulating the immune system by binding and inhibiting or enhancing its regulatory molecules thereby curing autoimmune and inflammatory diseases. White blood cells (B-lymphocytes) of the immune system in higher organisms produce antibodies which are large, glycoprotein molecules. The function of the antibodies is to recognise and attach matter harmful to the organism, thereby marking it out for other components of the immune system to destroy. The organism makes millions of different types of antibodies; each designed to bind a surface feature (the epitope or antigenic determinant) on the foreign body (the antigen). The most common human antibody, IgG, is shaped like the capital letter "Y", IgE, IgD, IgA, IgM are other types of antibodies Overtime, antibodies have been produced from the serum of animals. Serum contains a cocktail of antibodies (polyclonals), some of which will attach to the antigen. Since when Emil Behring, in1890, published a paper demonstrating that diphtheria antitoxin serum could protect against a lethal dose of diphtheria toxin; antisera has been used to neutralise pathogens in acute disease as well as prophylactically. Antisera is also widely used in vitro as a diagnostic tool to establish and monitor disease. The problem with using antisera for treatment is that it leads to "serum sickness" - basically the patient's immune system reacts against the harmful proteins causing fevers, rashes, joint pains and sometimes life-threatening anaphylactic shock. Also, the serum is a crude extract containing not only the antibodies against the disease-causing pathogen (often at low concentration), but also unrelated antibodies (plus other non-antibody proteins). In 1975, Csar Milstein and Georges Khler at the Medical Research Council's (MRC) Laboratory of Molecular Biology (LMB) in Cambridge (UK) developed a way to produce "custom-built" antibodies "in vitro" with relative ease. They injected rodent antibody producing cells with immortal tumour cells (myelomas) from the bone marrow of mice to produce a hybridoma. A hybridoma has the cancer's ability to reproduce almost indefinitely, plus the immune cell's ability to make antibodies. Once screened, to isolate the hybridomas producing antibodies of a determined antigen specificity and required affinity - and given the right nutrients - a hybridoma will grow and divide almost indefinitely, mass-producing antibodies of a single type (monoclonals). This resembled a production-line with batch consistency for Ehrlich's "magic bullets". For this breakthrough these scientists (Csar Milstein and Georges Khler) won the Nobel Prize in Medicine in 1984. Immuno-cytochemical staining has

Application Of Geographic Information System in Defense Organisations Essay

Application Of Geographic Information System in Defense Organisations (Army, Navy & Airforce) - Essay Example The future soldiers and powerful army will not be able to survive in information technology environment without any availability of information army and GIS. The advancement in army makes sure that modern maps are also present. In fact, the term ‘modern map’ not only mean an up to date map but also includes transparency (that is, being able to be used simply, from the user’s point of view) along with perfect accuracy. The higher-than-average information content is available in order to support military the special military aspects. There is no doubt that any extra element related to information may be needed in order to execute task, planning and implementation. The old maps will face disadvantage due to chase traditional methods. The old traditional method has changed; it is not applicable to complement standard topographic maps along with special information. Thus, in this manner creating thematic maps that helps to gather useless information of the user’ s. on the other hand, the essential mapping background is currently ‘adjusted’ in order to provide special information. ... In order to implement the defense task for the national security, public administration and society it is important to have all the information regarding artificial objects on surface and geometric information of natural objects. Moreover, we have also demonstrates the semantics related to events associated with the domain of remote sensing and image processing. Likewise, the events were incorporated with estimation of vegetation shield by consuming two indexes i.e. using Normalized Difference Vegetation Index (NDVI) and Ratio Vegetation Index (RVI). Moreover, along with these indexes, supervised and unsupervised classification is also conducted that is related to different information classes illustrated on an image. Moreover, these events also include images and pictures that are captured via satellites that are powered with remote sensing technology. The advantage of remote sensing is that it can detect objects in real time along with providing coverage of an expanded area within a short period of time. However, remote sensing can be divided in to two types i.e. active remote sensing and passive remote sensing. The active remote sensing provides an opportunity to be utilized at any time throughout the day and regardless of any season. Moreover, active remote sensing also facilitates the inspection of wavelengths that are not effectively illustrated by the Sun. In addition, it also takes charge of the illumination on the targeted object. On the other hand, passive remote sensing requires the Sun, in order to brighten the objective or the target. Moreover, this type of remote sensing uses reflected waves to measure the distance. As (Smith 2010) states that remote sensing based on active methodology needs a significant amount of energy source